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Two sequencing methods were used to measure genetic variants in malaria parasite yoelii yoelii, strain N67. High quality gold standard Sanger sequences were obtained for 45 amplicons, a small subset of the 14-chromosome genome. Next generation sequencing (NGS) was used to find genome-wide variants, but there is a lot more noise and so some false positive variants need to be filtered via thresholding the MQ score.

Usage

data("malaria")

Format

List of 8 data.frames: $ error.variants :'data.frame': 18800 obs. of 19 variables: $ regions :'data.frame': 14 obs. of 6 variables: $ amplicons :'data.frame': 45 obs. of 8 variables: $ chroms :'data.frame': 14 obs. of 2 variables: $ error.amplicons :'data.frame': 1800 obs. of 11 variables: $ filterVar.labels:'data.frame': 40 obs. of 3 variables: $ error.curves :'data.frame': 120 obs. of 4 variables: $ filterVar :'data.frame': 1 obs. of 2 variables:

Source

https://github.com/tdhock/malaria-evolution-viz